Chemicals that can help to reduce plaque formation
The Board of management with the help of mechanical processing is very time-consuming task, professionally managed or practiced personally. Satisfactory for home care requires further measure dexterity and high level of motivation, which many people do not possess. It is therefore not surprising that a large number of chemicals have been tested for their ability to reduce the accumulation of plaque. Some of the chemicals act by preventing colonization of enamel or the removal of attached organisms, but in General, these showed less than the promise of antimicrobial agents. in this section will be limited to a consideration of those chemicals which have been tested as a preventive means for their impact on the supragingival plaque accumulation.
Chemical antiplaque agents assessed in several ways: in vitro studies can be used to assess antimicrobial action, short-term studies of several days to assess the ability chemicals inhibit the formation of plaques in vivo; however, research 2-3 weeks needed to establish the inhibitory or therapeutic effect on gingivitis; and long-term studies unsupervised use in several months it is necessary to fully appreciate the subsidiary the value of the agent when used in combination with brushing.
Despite the broad spectrum antimicrobial agents with proven efficacy in the treatment of many different infections, nature plaque infection limits the usefulness of chemical agents. Great value and are, apparently, the specifics of chronic gingivitis and proliferative ability of bacteria in the mouth. Therefore, while various antiseptic mouthwashes can achieve a temporary reduction in the number of bacterial plaque, only those agents that are still active in her mouth to have a lasting effect after taking able significant plaque braking. Thus, cationic bisbiguanide, chlorhexidine, apparently, much more effective RAID-inhibitor in vivo than other antiseptics with equal or greater in vitro activity. Indeed, it is well known that antiplaque effect chlorhexidine is unsurpassed all other chemical agents. Phenolic substances (Listerine) and triclosan are moderately effective, while Quaternary ammonium compounds, salts of metals, fluorides, sanguinarine, oxygen agents, hexetidine, and enzymes are of little value.