Leukocyte Migration, Chemotaxis, and Phagocytosis
1. Leukocyte migration
of blood vessels
A. Transendothelial Migration
1. In order to fight infection, immune system cells travel through the blood and tissues (Fig. 8-9).
a. Next to the infection site, immune cells push their way between endothelial cells lining the blood vessels (hemorrhage) and type of connective tissue .
B. A thin layer of epithelial cells that line the inside of the blood vessels is called the endothelium. For this reason, the process of immune cells exit of ships and enter in the tissues is called transendothelial migration.
2. Defects in transendothelial migration associated with aggressive periodontitis, emphasizing the importance of this process in the defense against periodontal pathogens.
B. migration of leukocytes in the focus of infection
1. As soon as leukocytes type of connective tissue, the cells should go to the site of infection.
2. Chemotaxis is a process in which leukocytes attracts the source of infection in response to biochemical compounds released invading microorganisms.