Medications that Alter Plaque Biofilm Composition, pH, or Salivary Flow
The plaque A. Biofilms composition and pH
1. Many oral medications alter plaque biofilm composition and pH in the way
harmful for periodontal tissues.
2. Medicines That Contain Sugar
a. Sugar is the main component in some cough drops, liquid medications, cough syrups, tonics, chewable vitamins, antacid tablets, and other medications. Drugs that contain sugar, Add significantly changes the plaque biofilm pH and composition.
B. Sugar-containing liquid or chewing drugs are sometimes used for the treatment of children with chronic diseases. Parents should be aware of the oral health consequences of such drugs. Giving medications during meals instead of between meals useful.
c. Sugar is metabolized by bacteria, form acid, causing demineralization of enamel. Demineralized areas, are rude and to act as points for bacteria, keeping bacterial plaque biofilm against tissues and, ultimately, causing inflammation of the gums.
3. Medications that lower pH
Some over-the-counter (OTC) medicines contain sugar and vitamin C. this combination of sugar and vitamin C leads to acid pH.
B. Examples of foods containing sugar and vitamin C include chewable tablets of vitamin C tablets, some cough drops, and some liquid cough.
c. Products that change the plaque biofilm pH can result in significantly root surface caries in older age and affect the metabolism of periodontal pathogens [39,40].
B. salivary flow and pH
1. Adequate saliva flow is necessary for maintaining healthy tissues of the oral cavity. The ability of saliva to limit the growth of pathogenic microorganisms, is the main determinant of systemic and oral health.
a. The physical flow of saliva helps to expel microbes from the teeth and the mucous surfaces. Saliva may cause bacteria stick together, so that they can be swallowed, before they become firmly attached.
B. Saliva rich antibacterial components. Certain molecules in saliva can directly kill or inhibit various microbes.
2. Patients with xerostomia suffer from increased incidence of candidiasis of the oral cavity, crown and root surface of the teeth and the excess plaque biofilm formation.
3. More than 400 OTC and prescription drugs have xerostomia as a possible side effect [41,42].
4. Some of the most common groups of drugs that cause dry mouth are cardiovascular drugs (blood pressure, diuretics, calcium channel blockers); antidepressants, sedatives, analgesics Central action; ANTIPARKINSONISM medicines; allergies; and antacids .